| CPDD3721 | I-BEC HCl | I-BEC, eyaziwa ngokuba yi-S-(2-boronoethyl) -L-cysteine, i-inhibitor ye-Arginase II ebopha ngokukhawuleza kunye nokhuphiswano kunye ne-Ki ye-0.31 μM (ph 7.5). I-BEC iphakamisa kakhulu ukuphumla okuxhomekeke ku-NO-kuxhomekeka komntu kwi-penile corpus canvernosum imisipha egudileyo kwi-vitro ekugxininiseni phakathi kwe-0.1-1.0 mM. I-S-(2-boronoethyl) -L-cysteine ibophelela kwi-arginase njenge-analogue ye-transition state kunye nokuphucula ukuphumla kwemisipha epholileyo kwi-penile corpus cavernosum. |
