GDC-0077

Pangalan ng Kemikal:

(S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl)amino)propanamide

SMILES Code:

C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1

InChi Code:

InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11) 24)2 5-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26 )/t9-,12-/m0/s1

InChi Key:

SGEUNORSOZVTOL-CABZTGLSA-N

Keyword:

GDC-0077; GDC 0077; GDC0077

Solubility:DMSO

Imbakan: 

Paglalarawan:

Ang GDC-0077 ay isang oral na magagamit na PI3K inhibitor na may potensyal na aktibidad na antineoplastic. Ang GDC-0077 ay nakuha mula sa patent WO 2017001645 A1, formula I.

Target: PI3K