Ziftomenib;KO539

Jina:(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Nambari ya Katalogi:CPD113642

Nambari ya CAS:2134675-36-6

Uzito wa Masi:717.87

Mfumo wa Kemikali:C33 H42 F3 N9 O2 S2

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Maelezo ya Bidhaa

Lebo za Bidhaa

Ukubwa wa Pakiti	Upatikanaji	Bei (USD)
0.1G	Katika Hisa	650
0.5G	Katika Hisa	970
1G	Katika Hisa	1350

Jina la Kemikali:

(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Msimbo wa SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Msimbo wa InChi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2) 23(5-6-29(27)45)20-42-9-7-24(8-10-42)39-30-28-16-26(17-33(34,35)36)48- 31(28)41-32(38-3)40-30/h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40 ,41)/t21-/m0/s1

Ufunguo wa InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Neno muhimu:

2134675-36-6;CAS:2134675-36-6;CAS:2134675-36-6;Ziftomenib; KO539; KO 539; KO-539

Umumunyifu:Kuamuliwa

Hifadhi:Kavu, giza na kwa 0 - 4 C kwa muda mfupi (siku hadi wiki) au -20 C kwa muda mrefu (miezi hadi miaka).

Maelezo:

Ziftomenib (KO-539) ni kizuizi cha mwingiliano wa menin MLL na shughuli za mdomo.

Lengo: menin-MLL

Iliyotangulia: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

Inayofuata: N-Methyl-5-(piperazin-1-yl)picolinamide hidrokloridi