VU0448088 (ML253)

Jina la Kemikali:

3-amino-5-kloro-4,6-dimethyl-N-(pyridin-4-ylmethyl)thieno[2,3-b]pyridine-2-carboxamide

Msimbo wa SMILES:

CC1=NC2=C(C(N)=C(S2)C(NCC3=CC=NC=C3)=O)C(C)=C1Cl

Msimbo wa InChi:

InChI=1S/C16H15ClN4OS/c1-8-11-13(18)14(23-16(11)21-9(2)12(8)17)15(22)20-7-10-3-5- 19-6-4-10/h3-6H,7,18H2,1-2H3,(H,20,22)

Ufunguo wa InChi:

XNCQMFVABACABG-UHFFFAOYSA-N

Neno muhimu:

1417616-42-2;CAS:1417616-42-2;CAS:1417616-42-2;VU0448088;ML253;ML 253;ML-253

Umumunyifu: 

Hifadhi: 

Maelezo:

VU0448088 (ML253) ni moduli bora chanya ya allosteric ya tricyclic muscarinic acetylcholine receptor subtype 4 (M4) ambayo inaweza kuvuka kizuizi cha damu-ubongo.

Lengo: aina ndogo ya 4 ya kipokezi cha tricyclic muscarinic acetylcholine (M4)