PAKA # | Jina la Bidhaa | Maelezo |
CPD111306 | 7-bromo-2,4,6-trichloro-8-fluoroquinazoline | |
CPD113109 | ARS-1323-Alkyne | ARS-1323-alkyne, kizuia-II mfukoni (S-IIP) |
CPDP801183 | VVD-214;RO7589831;VVD-133214 | VVD-214 ni kizuizi cha sintetiki cha WRN helicase lethal allosteric. |
CPDP801366 | Inlexisertib;DCC-3116 | DCC-3116 ni kizuizi kinachofanya kazi kwa mdomo cha ULK1/2. |
CPDA601378 | Nonylacridine Orange | |
CPD112537 | 4H-1,3-Dioxolo[4,5-c]pyrrole-4-carboxylic acid,... | |
CPDP801763 | MC3138 | MC3138 ni kuwezesha kuchagua SIRT5. |
CPDP801758 | Chk1-IN-6 | Chk1-IN-6 ni kizuizi chenye nguvu, cha kuchagua, na kinachopatikana kwa mdomo cha CHK1. |
CPD113410 | NDI-101150 | NDI-101150 ni kizuizi chenye nguvu na cha kuchagua cha HPK1 (kinase ya seli ya hematopoietic progenitor 1). |
CPDA601453 | BMS-986408 | BMS-986408 ni kizuizi cha DGK α/Zeta kinachofaa kwa mdomo. |
CPDA601445 | AZD0780;EX-A6975;laroprovstatum; laroprovstat | PCSK9-IN-12 ni mchanganyiko wa hetermatic. PCSK9-IN-12 ina mshikamano unaofunga kwa PCSK9 yenye thamani ya Kd<200 nM. PCSK9-IN-12 inaweza kutumika kwa ajili ya utafiti wa kimetaboliki ya cholesterol. |
CPDA601447 | PF07328948 | PF-07328948 ni kizuizi cha mdomo cha BDK (ketone dehydrogenase kinase) chenye mnyororo wa matawi. |
CPD112881 | (1S)-2,2,2-trifluoro-1-methylethyl]hydrazine hy... | |
CPD108261 | LOXO-305;LY 3527727;Pirtobrutinib | Pirtobrutinib (LOXO-305) ni kizuizi cha BTK cha kizazi kijacho cha kuchagua sana na kisicho na ushirikiano ambacho kinaweza kuzuia mabadiliko mbalimbali ya BTK C481. |
CPD115335 | Luxdegalutamide; ARV-766 | Luxdegalutamide (ARV-766) ni hidrolisisi ya protini inayolengwa kwa hidrolisisi (PROTAC) inayolenga vipokezi vya androjeni (AR), ambayo inaweza kudhoofisha mabadiliko yanayohusiana na upinzani wa AR. |
CPDA601356 | iHSP110-33 | |
CPDP800487 | TNG462 | TNG-462 ni kizuizi cha kuchagua PRMT5 kinachofaa kwa mdomo. |
CPDP801649 | 1,2,4-Triazolo[4,3-c]pyrimidine-5,8-diamine, N5... | EED ligand 1 ni kizuizi tofauti na bora ambacho kinalenga kitengo kidogo cha EED cha methyltransferase PRC2. |
CPDM400208 | 6,7-Difluoro-4(3H)-quinazolinone | |
CPDP801752 | N-(4-quinolinylcarbonyl)Glycine | |
CPDM400190 | Methyl 5-bromo-2-methyl-3-(trifluoromethyl) benz... | |
CPDP800126 | IDE397 (GSK-4362676) | |
CPDP801185 | NST-628 | NST-628 ni njia ya MAPK jeli ya molekuli yenye upenyezaji wa kizuizi cha damu-ubongo, ambayo inaweza kuzuia fosforasi ya RAF na kuwezesha MEK. |
CPD115153 | NX-2127 | NX-2127 ni kizuizi cha mdomo cha BTK. |