Vardenafil

Jina la Kemikali:

2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propyl-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a][1,3,5]triazin-4-moja

Msimbo wa SMILES:

O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)[N]4(C)C3=CN(CCC)C4

Msimbo wa InChi:

InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20( 19)33-7-3)34(31,32)28-13-11-26(6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2, 1-4H3,(H,24,25,30)

Ufunguo wa InChi:

UWRWYSQUBZFWPU-UHFFFAOYSA-N

Neno muhimu:

Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4

Umumunyifu:Mumunyifu katika DMSO

Hifadhi:0 - 4°C kwa muda mfupi (siku hadi wiki), au -20°C kwa muda mrefu (miezi)

Maelezo:

Vardenafil, pia inajulikana kama BAY 38-9456, ni kizuizi cha PDE5 kinachotumika kutibu dysfunction ya erectile. Dalili za Vardenafil na contra-dalili ni sawa na inhibitors nyingine za PDE5; inahusiana kwa karibu katika kazi ya sildenafil citrate (Viagra) na tadalafil (Cialis). Tofauti kati ya molekuli ya vardenafil na sildenafil citrate ni nafasi ya atomi ya nitrojeni na mabadiliko ya kikundi cha methyl pete ya sildenafil ya piperazine hadi kikundi cha ethyl. Tadalafil ni tofauti kimuundo na sildenafil na vardenafil. Muda mfupi wa ufanisi wa Vardenafil unalinganishwa na lakini mrefu zaidi ya sildenafil.

Lengo: PDE5