Luxdegalutamide; ARV-766

Jina:4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamide

Nambari ya Katalogi:CPD115335

Nambari ya CAS:2750830-09-0

Uzito wa Masi:807.95

Mfumo wa Kemikali:C45 H54 F N7 O6

Kwa utafiti wa kisayansi tu, sio kwa wagonjwa.

Tutumie barua pepe Pakua kama PDF

Maelezo ya Bidhaa

Lebo za Bidhaa

Ukubwa wa Pakiti

Upatikanaji

Bei (USD)

Jina la Kemikali:

4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamide

Msimbo wa SMILES:

CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(C(N[C@@H]6C(=O)NC(=O) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1

Msimbo wa InChi:

InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)58-5)50- 39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23-21-51)32- 11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28,36, 42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0/s1

Ufunguo wa InChi:

RDPPBRKNBBXPNZ-FMPIRMQTSA-N

Neno muhimu:

2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0;ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide

Umumunyifu:

Hifadhi:Kavu, giza na kwa 0 - 4 C kwa muda mfupi (siku hadi wiki) au -20 C kwa muda mrefu (miezi hadi miaka).

Maelezo:

Luxdegalutamide (ARV-766) ni hidrolisisi ya protini inayolengwa kwa hidrolisisi (PROTAC) inayolenga vipokezi vya androjeni (AR), ambayo inaweza kudhoofisha mabadiliko yanayohusiana na upinzani wa AR.

Lengo: AR

Iliyotangulia: iHSP110-33

Inayofuata: LOXO-305;LY 3527727;Pirtobrutinib