LOXO-305;LY 3527727;Pirtobrutinib

Jina la Kemikali:

(S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide

Msimbo wa SMILES:

O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N

Msimbo wa InChi:

InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32 )(H,29,33)/t11-/m0/s1

Ufunguo wa InChi:

FWZAWAUZXYCBKZ-NSHDSACASA-N

Neno muhimu:

2101700-15-4;CAS:2101700-15-4;CAS:2101700-15-4;LOXO-305;LOXO 305;LOXO305;LY 3527727;LY-3527727;LY3527727b;

Umumunyifu: 

Hifadhi:Kavu, giza na kwa 0 - 4 C kwa muda mfupi (siku hadi wiki) au -20 C kwa muda mrefu (miezi hadi miaka).

Maelezo:

Pirtobrutinib (LOXO-305) ni kizuizi cha BTK cha kizazi kijacho cha kuchagua sana na kisicho na ushirikiano ambacho kinaweza kuzuia mabadiliko mbalimbali ya BTK C481.

Lengo: BTK