AZD4547
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 1g | E teng thepeng e teng ka lebenkeleng | 750 |
| 5g | E teng thepeng e teng ka lebenkeleng | 3000 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide
SMILES Khouto:
O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4 )C=C3
Khoutu ea InChi:
InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21( 29-30-25)8-5 -19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,( H2,28,29,30,32)/t17-,18+
InChi Key:
VRQMAABPASPXMW-HDICACEKSA-N
Keyword:
AZD4547, AZD-4547, AZD 4547, 1035270-39-3
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
AZD 4547 ke inhibitor e khethiloeng ea fibroblast growth factor receptor (FGFR) tyrosine kinase e nang le litekanyetso tsa IC50 tsa 0.2, 2.5, le 1.8 nM bakeng sa FGFR1, 2, le 3, ka ho latellana.
Sepheo: FGFR
