H3B-6527
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 500 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 775 |
| 1g | E teng thepeng e teng ka lebenkeleng | 1750 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl) phenyl)acrylamide
SMILES Khouto:
C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C) =C3)=O
Khoutu ea InChi:
InChI=1S/C29H34Cl2N8O4/c1-6-25(40)35-20-14-18(39-12-10-38(7-2)11-13-39)8-9-19(20)34- 23-16-24(33-17-32-23)37(3 )29(41)36-28-26(30)21(42-4)15-22(43-5)27(28)31/h6,8-9,14-17H,1,7,10-13H2 ,2-5H3,(H,35,40)(H,36,41)(H,32,33,34)
InChi Key:
MBWRLLRCTIYXDW-UHFFFAOYSA-N
Keyword:
H3B-6527, H3B 6527, H3B6527, 1702259-66-2
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
H3B-6527 (H3 Biomedicine) ke FGFR4 inhibitor e khethiloeng ka ho fetisisa e nang le ts'ebetso e matla ea antitumour ho FGF19 amplified cell line le litoeba.
Sepheo: FGFR4
