BAY-293

Lebitso la lik'hemik'hale:

(R) -6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

SMILES Khouto:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

Khoutu ea InChi:

InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22(30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28 ,29)/t15-/m1/s1

InChi Key:

WEGLOYDTDILXDA-OAHLLOKOSA-N

Keyword:

BAY-293,BAY 293,BAY293

Sollubility: 

Polokelo: 

Tlhaloso:

BAY-293 ke SOS1 inhibitor e matla e thibelang ts'ebetso ea RAS ka tšitiso ea tšebelisano ea RAS-SOS1. BAY-293) ka boikhethelo e thibela ho sebelisana ha KRAS-SOS1 le IC50 ea 21 nM 'me ke lipatlisiso tsa bohlokoa tsa lik'hemik'hale bakeng sa lipatlisiso tsa nako e tlang.

Sepheo: SOS1 inhibitor