AZD-7594
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
Boholo ba Pakete | Ho fumaneha | Theko (USD) |
100mg | E teng thepeng e teng ka lebenkeleng | 500 |
500mg | E teng thepeng e teng ka lebenkeleng | 800 |
1g | E teng thepeng e teng ka lebenkeleng | 1200 |
Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
3-(5-((1R,2S)-2-(2,2-difluoroproropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl) propoxy)-1H-indazol -1-yl)-N-(tetrahydrofuran-3-yl)benzamide
SMILES Khouto:
O=C(NC1COCC1)C2=CC=CC(N3N=CC4=C3C=CC(O[C@H](C5=CC=C(OCCO6)C6=C5)[C@@H](NC(C( F)(F)C)=O)C)=C4)=C2
Khoutu ea InChi:
InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27) 44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11- 41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23? ,29-/m0/s1
InChi Key:
ZZWJKLGCDHYVMB-QMQODZDESA-N
Keyword:
AZD-7594, AZD 7594, AZD7594, AZ13189620, AZ-13189620, AZ 13189620, 1196509-60-0
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
AZD-7594, eo hape e tsejoang e le AZ13189620, ke modulator e hemang e khethang ea glucocorticoid receptor (GCCR). AZD-7594 e mokhahlelong oa II oa liteko tsa bongaka ke AstraZeneca bakeng sa kalafo ea asthma e bobebe ho isa ho e itekanetseng. E boetse e le litekong tsa kliniki tsa mohato oa I bakeng sa phekolo ea boloetse bo sa foleng ba pulmonary (COPD).
Sepheo: GCCR