AMG-510
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 1g | e teng thepeng e teng ka lebenkeleng | 1300 |
| 5g | e teng thepeng e teng ka lebenkeleng | 6000 |
| 10g | e teng thepeng e teng ka lebenkeleng | 10500 |
Lebitso la lik'hemik'hale:
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl) )pyrido[2,3-d]pyrimidin-2(1H)-one
SMILES Khouto:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
Khoutu ea InChi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
InChi Key:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Keyword:
AMG-510; AMG 510; AMG510
Sollubility:
Polokelo:
Tlhaloso:
AMG-510 ke KRAS G12C covalent inhibitor e matla. AMG-510 e ikhethela phetoho ea KRAS p.G12C, e ka ba boemong ba DNA, RNA kapa protheine, 'me e thibela, ka mokhoa o ntseng o e-so hlakisoe, pontšo ea le/kapa tumor cell signing ka KRAS p.G12C mutant. Sena se ka thibela kholo ea lisele tsa tumor tsa KRAS p.G12C
Sepheo: KRAS
