ABBV-744

Lebitso la lik'hemik'hale:

N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H -pyrrolo[2,3-c]pyridine-2-carboxamide

SMILES Khouto:

O=C(C(N1)=CC(C(C2=CC(C)(O)C)=CC=C2OC3=C(C)C=C(F)C=C3C)=CN4C)=C1C4 =O)NCC

Khoutu ea InChi:

InChI=1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28( 4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3, (H,30,33)

InChi Key:

OEDSFMUSNZDJFD-UHFFFAOYSA-N

Keyword:

ABBV-744, ABBV 744, ABBV744, 2138861-99-9

Sollubility:E qhibiliha ka DMSO

Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).

Tlhaloso:

ABBV-744 ke BDII e khethang BET bromodomain inhibitor e ntseng e batlisisoa ho alafa AML le mofetše oa tšoelesa oa senya o hananang le metastic castration.

Sepheo: BET bromodomain