ARS-1620
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 800 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 1500 |
| 1g | E teng thepeng e teng ka lebenkeleng | 2000 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Khouto:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
Khoutu ea InChi:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Keyword:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
ARS-1620 ke prodrug e entsoeng ho tloha ARS-853, e matla le e khethang ea S-IIP G12C inhibitor. ARS-1620 e lebelletsoe ho ba leano la kalafo bakeng sa mofets'e oa p.G12C KRAS o fetohang.
Sepheo: KRAS (K-Ras G12C)
