BAZ2-ICR
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 500 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 800 |
| 1g | E teng thepeng e teng ka lebenkeleng | 1200 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
SMILES Khouto:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
Khoutu ea InChi:
InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27) 17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
InChi Key:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
Keyword:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
BAZ2-ICR ke probe e babatsehang ea lik'hemik'hale bakeng sa lithuto tse sebetsang tsa BAZ2 bromodomains in vitro le in vivo. Bromodomain e nang le liprotheine tsa BAZ2A/B e bapala karolo ea bohlokoa ho lokisoeng ha chromatin le taolong ea li-RNA tse sa tsitsang. BAZ2-ICR e na le IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; solubility 25 mm (D2O) le F = 70%.
Sepheo: BAZ2