Osimertinib Mesylate
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 500mg | E teng thepeng e teng ka lebenkeleng | 100 |
| 1g | E teng thepeng e teng ka lebenkeleng | 180 |
| 5g | E teng thepeng e teng ka lebenkeleng | 600 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino )phenyl)acrylamide mesylate
SMILES Khouto:
CN(CCN(C)C)C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2 .OS(=O)(C)=O
Khoutu ea InChi:
InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3) 32-28-29-13-12-21(31-28 )20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2 -6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
InChi Key:
FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Keyword:
AZD-9291, AZD9291, AZD 9291, Tagrisso,Osimertinib Mesylate, 1421373-66-1
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
Osimertinib, eo hape e tsejoang e le mereletinib le AZD-9291, ke moloko oa boraro oa EGFR inhibitor, o bontšitse tšepiso lithutong tsa pele ho nako 'me o fana ka tšepo ho bakuli ba nang le kankere ea matšoafo e tsoetseng pele e seng e hanyetsana le li-inhibitors tsa EGFR tse teng. AZD9291 e sebetsa haholo mefuteng ea preclinical mme e mamelloa hantle mefuteng ea liphoofolo. E thibela liphetoho tsa EGFR tse sebetsang le tse hanyetsanang ha li ntse li boloka mofuta o tloaelehileng oa EGFR o teng liseleng tse tloaelehileng tsa letlalo le mala, kahoo e fokotsa litla-morao tse amanang le meriana e teng hona joale. Osimertinib e amohetsoe ka Nov. 2015.
Sepheo: EGFR
