THZ2

THZ2
  • Magaca:THZ2
  • Lambarka buugga:CPDB1587
  • Lambarka CAS:1604810-84-5
  • Miisaanka Molecular:566.06
  • Foomka Kiimikada:C31H28ClN7O2
  • Cilmi baaris cilmiyeed oo keliya, ma ahan bukaanka.

    Faahfaahinta Alaabta

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    Cabbirka Xidhmada Helitaanka Qiimaha (USD)
    100mg In Stock 500
    500mg In Stock 800
    1g In Stock 1200
    Cabiro badan Hel Xigasho Hel Xigasho

    Magaca Kiimikada:

    N-[3-[[5-chloro-4--(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E) -4-(dimethylamino) laakiin-2- enoyl]amino]benzamide

    Koodhka dhoola cadeynta:

    O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2=C1)C5=CC=CC(NC(/C=C/CN) (C)C)=O)=C5

    Koodhka InChi:

    InChi=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6- 11-23 (17-22)37-31-34-19-26 (32)29 (38-31)25-18-33-27-13-4-3-12-24 (25)27/h3- 14,16-19,33H,15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b14-7+

    Furaha InChi:

    FONRCZUZCHXWBD-VGOFMYFVSA-N

    Ereyga muhiimka ah:

    THZ-2, THZ 2, THZ2, 1604810-84-5

    Xalka:Ku milmay DMSO

    Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

    Sharaxaad:

    THZ2, analooga ah THZ1, oo leh suurtogalnimada in lagu daaweeyo kansarka naasaha ee Triple-negative (TNBC), waa awood iyo xushay CDK7 inhibitor kaas oo ka adkaada xasilloonida THZ1 ee vivo. IC50: CDK7= 13.9 nM; Unugyada TNBC= 10 nM

    Ujeedka: CDK


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