THZ2
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
100mg | In Stock | 500 |
500mg | In Stock | 800 |
1g | In Stock | 1200 |
Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
N-[3-[[5-chloro-4--(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E) -4-(dimethylamino) laakiin-2- enoyl]amino]benzamide
Koodhka dhoola cadeynta:
O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2=C1)C5=CC=CC(NC(/C=C/CN) (C)C)=O)=C5
Koodhka InChi:
InChi=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6- 11-23 (17-22)37-31-34-19-26 (32)29 (38-31)25-18-33-27-13-4-3-12-24 (25)27/h3- 14,16-19,33H,15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b14-7+
Furaha InChi:
FONRCZUZCHXWBD-VGOFMYFVSA-N
Ereyga muhiimka ah:
THZ-2, THZ 2, THZ2, 1604810-84-5
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).
Sharaxaad:
THZ2, analooga ah THZ1, oo leh suurtogalnimada in lagu daaweeyo kansarka naasaha ee Triple-negative (TNBC), waa awood iyo xushay CDK7 inhibitor kaas oo ka adkaada xasilloonida THZ1 ee vivo. IC50: CDK7= 13.9 nM; Unugyada TNBC= 10 nM
Ujeedka: CDK