Riviciclib
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
2- (2-chlorophenyl) -5,7-dihydroxy-8-((2R,3S)-2- (hydroxymethyl) -1-methylpyrrolidin-3-yl) -4H-chromen-4-hal hydrochloride
Koodhka dhoola cadeynta:
O=C1C=C(C2=CC=CC=C2Cl)OC3=C1C(O)=CC(O)=C3[C@H]4[C@H](CO)N(C)CC4.[H] Cl
Koodhka InChi:
InChi=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28- 21 (19) 20) 11-4-2-3-5-13 (11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12 -,14+;/m1./s1
Furaha InChi:
OOVTUOCTLAERQD-OJMBIDBESA-N
Ereyga muhiimka ah:
P276-00; P-276-00; P 276-00; P-27600; P 27600; P 27600; Riviciclib, Riviciclib HCl
Xalka:
Kaydinta:
Sharaxaad:
Riviciclib, oo sidoo kale loo yaqaan P276-00, waa flavone iyo kinase ku tiirsan cyclin (CDK) oo leh firfircoonida antineoplastic ee suurtagalka ah. P276-00 waxay si xushmad leh u xidhaa oo joojisaa Cdk4/cyclin D1, Cdk1/cyclin B iyo Cdk9/cyclin T1, serine/threonine kinases oo door muhiim ah ka ciyaara nidaaminta wareegga unugyada iyo kororka unugyada. Joojinta kinase-yadani waxay keenaysaa in la xiro wareegga unugyada inta lagu jiro kala-guurka G1/S, taas oo horseedaysa induction of apoptosis, iyo xakameynta kororka unugyada burooyinka.
Ujeedka: CDK