CAT # | Magaca Alaabta | Sharaxaada |
CPD100230 | JBJ-04-125-02 R-isomer | |
CPD3232 | NTN21277 | NTN21277, oo sidoo kale loo yaqaan Gefitinib-based PROTAC 3 waa VHL-qorista PROTAC taas oo keenta hoos u dhaca EGFR iyo EGFR mutants oo leh DC50 ee 11.7 nM iyo 22.3 nM ee unugyada HCC827 (Exon 19 del) iyo unugga H3258R (L). |
CPDB3615 | Nazartinib; EGF816; NVS-816 | Nazartinib, oo sidoo kale loo yaqaan EGF816 iyo NVS-816, waa af laga heli karo, aan laga noqon karin, jiilka saddexaad, mutant-doortay korriinka koritaanka epidermal (EGFR), oo leh firfircoonida antineoplastic. |
CPDB0934 | EAI-045 | EAI045 waa mid awood leh oo doorta EGFR horjooge. EAI045 waxay beegsataa doorsoon mutants EGFR u adkaysta daawada laakiin waxay u tudhaysaa soo dhawaynta nooca duurjoogta ah. EAI045 waxay joojisaa L858R/T790M-mutant EGFR oo leh awood hoose oo nanomolar ah oo ku jirta qiimaynta biochemical. |
CPDB0101 | Poziotib | Daawooyinka ay ku jiraan poziotinib ayaa lagu hayaa baadhitaano tijaaboyin caafimaad oo loogu talagalay daawaynta EGFR-mutant adenocarcinoma sambabada. |
CPDB0137 | Osimertinib Mesylate | Osimertinib, oo sidoo kale loo yaqaan mereletinib iyo AZD-9291, waa jiilka saddexaad ee EGFR inhibitor, wuxuu muujiyay ballan-qaadka daraasadaha saxda ah wuxuuna rajo ka qabaa bukaannada qaba kansarka sambabada sare kuwaas oo u adkeysanaya inhibitors EGFR ee jira. |