| CAT # | Magaca Alaabta | Sharaxaada |
| CPD100464 | Erdafitinib | Erdafitinib, oo sidoo kale loo yaqaan JNJ-42756493, waa awood xoog leh oo la dooran karo oo afka laga heli karo, pan-fibroblast factor receptor (FGFR) inhibitor oo leh firfircoonida antineoplastic. Marka la maamulo afka, JNJ-42756493 waxay ku xidhan tahay oo ay joojisaa FGFR, taas oo keeni karta in la joojiyo dariiqyada gudbinta calaamadaha FGFR ee la xidhiidha iyo sidaas awgeed xannibaadda kordhinta unugyada burooyinka iyo dhimashada unugyada burooyinka ee FGFR-soo-saarka unugyada burooyinka. FGFR, oo lagu hagaajiyay noocyo badan oo unugyo burooyin ah, ayaa ah reseptor tyrosine kinase lagama maarmaan u ah kororka unugyada burooyinka, kala duwanaanta iyo badbaadada. |
| CPD3618 | TAS-120 | TAS-120 waa xannibaadaha afka laga heli karo ee soo-dhoweeyaha koritaanka fibroblast (FGFR) oo leh firfircoonida antineoplastic ee suurtagalka ah. FGFR inhibitor TAS-120 ayaa si xushmad leh oo aan leexleexad lahayn u xidhaa oo joojisa FGFR, taas oo keeni karta in la joojiyo labadaba dariiqa gudbinta calaamada dhexdhexaadka ah ee FGFR iyo kororka unugyada burooyinka, iyo korodhka dhimashada unugyada ee FGFR-gacanta unugyada burooyinka. FGFR waa tayroosin kinase reseptor ah oo lagama maarmaan u ah kororka unugyada burooyinka, kala soocida iyo badbaadada iyo muujinteeda ayaa lagu hagaajiyay noocyo badan oo unugyo burooyin ah. |
| CPDB1093 | Derazantinib; ARQ-087 | Derazantinib, oo sidoo kale loo yaqaan ARQ-087, waa xannibaadaha afka laga heli karo ee soo-dhoweeyaha koritaanka fibroblast (FGFR) oo leh firfircoonida antineoplastic ee suurtagalka ah. |
| CPDB0942 | BLU-554 | BLU-554 waa fayraska koritaanka fibroblast 4 (FGFR4) inhibitor oo awood u leh daaweynta kansarka hepatocellular iyo cholangiocarcinoma. |
| CPD0999 | H3B-6527 | H3B-6527 (H3 Biomedicine) waa horjooge FGFR4 aadka loo xushay oo leh firfircoonida antitumour ee FGF19 ee xadhkaha gacanta iyo jiirarka. |
| CPD0997 | FGF401 | FGF-401 waa horjooge FGFR4 ah oo laga soosaaray patent WO2015059668A1, tusaale isku dhafan 83; wuxuu leeyahay IC50 oo ah 1.9 nM. |
| CPDB0053 | AZD4547 | AZD 4547 waa horjooge door ah oo ka mid ah soo-dhoweeyaha koritaanka fibroblast (FGFR) tyrosine kinase oo leh IC50 qiimaha 0.2, 2.5, iyo 1.8 nM ee FGFR1, 2, iyo 3, siday u kala horreeyaan. |
| CPD3610 | BLU-9931 | BLU9931 waa mid awood leh, la xushay, oo aan laga noqon karin FGFR4 horjooge leh IC50 ee 3 nM, qiyaastii 297-, 184-, iyo 50-laab xulashada FGFR1/2/3, siday u kala horreeyaan. |
