Trelagliptin

Chemical Name:

(R) -2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

SMILES Kodhi:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

InChi Code:

InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14( 19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1

InChi Key:

IWYJYHUNXVAVAA-OAHLLOKOSA-N

Keyword:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

Tsanangudzo:

Trelagliptin, inozivikanwawo seSYR-472, ndeye refu inobata dipeptidyl peptidase-4 (DPP-4) inhibitor iyo iri kugadzirwa neTakeda mukurapa chirwere cheshuga chechipiri (T2D). Kamwe-vhiki nevhiki SYR-472 kurapwa kwakagadzirwa nekiriniki uye nenhamba yakakosha kuvandudzwa mukudzora glycemic muvarwere vane Type 2 chirwere cheshuga. Yakatenderwa zvakanaka uye inogona kunge iri nzira nyowani yekurapa kune varwere vane chirwere ichi. Trelagliptin (Zafatek(®)) yakabvumidzwa muJapan kurapa rudzi rwechipiri chirwere cheshuga mellitus (T2DM).

Chinangwa: DPP-4