Linagliptin

Chemical Name:

8--[(3R)-3-aminopiperidin-1-yl]-7-(asi-2-yn-1-yl)-3- methyl-1-[(4-methylquinazolin-2-yl)methyl]-3 ,7-dihydro-1H-purine-2,6-dione

SMILES Kodhi:

O=C(N1CC2=NC(C)=C3C=CC=CC3=N2)N(C)C4=C(N(CC#CC)C(N5C[C@H](N)CCC5)=N4)C1 =O

InChi Code:

InChI=1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35) 33(23(21 )34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15,26H2 ,1-3H3/t17-/m1/s1

InChi Key:

LTXREWYXXSTFRX-QGZVFWFLSA-N

Keyword:

Linagliptin, BI-1356, BI 1356, BI1356, 668270-12-0

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

Tsanangudzo:

Linagliptin, inozivikanwawo seBI-1356, ndeye DPP-4 inhibitor yakagadziriswa naBoehringer Ingelheim kurapa chirwere cheshuga chechipiri. Linagliptin (kamwe chete pazuva) yakabvumidzwa neUS FDA musi wa2 Chivabvu 2011 kurapwa kwechirwere cheshuga chechipiri. Iri kutengeswa naBoehringer Ingelheim naLilly.

Chinangwa: DPP-4