Omarigliptin

Chemical Name:

(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H -pyran-3-amine

SMILES Kodhi:

N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1

InChi Code:

InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1

InChi Key:

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

Keyword:

Omarigliptin,MK-3102,MK3102,Marizev,1226781-44-7

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

Tsanangudzo:

Omarigliptin, inozivikanwawo seMK-3102, ine simba uye inogara kwenguva refu DPP-4 inhibitor yekamwe-vhiki kurapwa kwechirwere cheshuga 2. MK-3102 (omarigliptin), yakaonekwa seine simba uye inosarudza dipeptidyl peptidase 4 (DPP-4) inhibitor ine yakanakisa pharmacokinetic mbiri inogoneka kune kamwe-vhiki dosing yevanhu uye yakasarudzwa semumiriri wekuvandudza kiriniki. Omarigliptin parizvino iri muchikamu chechitatu chekuvandudzwa kwekiriniki.

Chinangwa: DPP-4