Ozanimod

Chemical Name:

(S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 -isopropoxybenzonitrile

SMILES Kodhi:

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

InChi Code:

InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1- 2H3/t20-/m0/s1

InChi Key:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

Keyword:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

Tsanangudzo:

Ozanimod inosarudza, inowanikwa nemuromo modulator ye sphingosine-1-phosphate (S1P) receptors S1P1 uye SIP5. Inokonzera mukati meS1P1, inoderedza kutenderera kweB uye CCR7 (+) T lymphocytes, uye inoderedza kuputika uye zvirwere zvechirwere mumatatu ezvirwere zvekudzivirira muviri.1 Ozanimod iri mumakiriniki ekuedzwa kwekudzokazve multiple sclerosis uye ulcerative colitis.

Chinangwa: S1P