DEL-22379

DEL-22379
  • Zita:DEL-22379
  • Catalog Nhamba:CPDB3713
  • Nhamba yeCAS:181223-80-3
  • Molecular Weight:444.55
  • Chemical Formula:C26H28N4O3
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    100mg Mudura 350
    250mg Mudura 600
    1g Mudura 1200
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    (Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide

    SMILES Kodhi:

    O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5

    InChi Code:

    InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26(22)32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2, 1H3,(H,28,31)(H,29,32)/b22-13+

    InChi Key:

    INQUULXCZAKMS-LPYMAVHISA-N

    Keyword:

    DEL-22379, DEL22379, DEL 22379, 181223-80-3

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

    Tsanangudzo:

    DEL-22379 ine simba uye inosarudza ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization pasina kukanganisa ERK phosphorylation, inodzivirira tumorigenesis inotungamirirwa neRAS-ERK nzira oncogenes. Inenge 50% yezvakaipa zvevanhu zvinoratidza kusagadziriswa kweRAS-ERK kusaina; kuidzivisa inzira inoshanda yeantineoplastic kupindira.

    Chinangwa: ERK


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