LX-2761
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 500 |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1200 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
N-(1-((2-(Dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R), 5S,6R) -3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)-butanamide
SMILES Kodhi:
O=C(NC(C)(C)C(NCCN(C)C)=O)CCCC1=CC=C(CC2=CC([C@H]3[C@H](O)[C@@ H](O)[C@H](O)[C@@H](SC)O3)=CC=C2C)C=C1
InChi Code:
InChI=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20)18-22- 13-11-21(12-14-22)8-7-9-25(36)34-32(2,3)31(40)33-16-17-35(4)5/h10-15, 19,26-30,37-39H,7-9,16-18H2,1-6H3,(H,33,40)(H,34,36)/t26-,27-,28+,29+,30 -/m1/s1
InChi Key:
BNPZTRDIESRGTC-IXYVTWBDSA-N
Keyword:
LX-2761, LX2761, LX 2761, 1610954-97-6
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
LX2761 inzvimbo inobata SGLT1 inhibitor ine simba zvakanyanya mu vitro uye inononoka kunyura mudumbu glucose mu vivo kuvandudza glycemic control. LX2761 ine hSGLt1 2.2 nM; hSGLT2 2.7 nM uye F% =<2. LX2761 imorekuru rine simba, rakagadzikana mumakemikari, uye rakadzivirirwa rakawana humbowo hwepfungwa muOGTT pamitengo yakaderera. LX2761 yakagadzirirwa kuramba iri mumatumbo mushure mekusununguka kwemuromo kuti inhibit SGLT1 munharaunda pasina kukanganisa SGLT1 / 2 nzira muitsvo.
Chinangwa: SGLT1
