CB-839

CB-839
  • Zita:CB-839
  • Catalog Nhamba:CPDB1593
  • Nhamba yeCAS:1439399-58-2
  • Molecular Weight:571.57
  • Chemical Formula:C26H24F3N7O3S
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    100mg Mudura 500
    500mg Mudura 800
    1g Mudura 1200
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl)acetamide

    SMILES Kodhi:

    O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4

    InChi Code:

    InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8- 9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38)

    InChi Key:

    PRAAPINBUWJLGA-UHFFFAOYSA-N

    Keyword:

    CB-839, CB839, CB 839, 1439399-58-2

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

    Tsanangudzo:

    "CB-839 an olly bioavailable inhibitor ye glutaminase, ine inogona kuita antineoplastic basa. Pamusoro pekutonga kwemuromo, CB-839 inosarudza uye isingachinji inodzivisa glutaminase, enzyme ye mitochondrial inokosha pakushandurwa kweamino acid glutamine nekuvhara glutamine. kushandiswa, kuwanda mumasero ari kukurumidza kukura anokanganisa mamota anoenderana neGlutamine anovimba nekushandurwa kwe glutamine yekunze kuita glutamate uye glutamate metabolites kuti ape simba uye kugadzira zvivharo zvekugadzira macromolecules, anodiwa pakukura uye kurarama.

    Chinangwa: Glutaminase


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