BAZ2-ICR
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
100mg | Mudura | 500 |
500mg | Mudura | 800 |
1g | Mudura | 1200 |
Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
SMILES Kodhi:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
InChi Code:
InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27) 17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
InChi Key:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
Keyword:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
BAZ2-ICR yakanakisa kemikari probe yezvidzidzo zvinoshanda zveBAZ2 bromodomains in vitro uye in vivo. Iyo bromodomain ine mapuroteni BAZ2A/B inotamba mabasa akakosha mukugadzirisa chromatin uye kudzora kweasina kukodha maRNA. BAZ2-ICR ine IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; solubility 25 mM (D2O) uye F = 70%.
Chinangwa: BAZ2