AZD8186
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 350 |
| 500mg | Mudura | 700 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
(R)-8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide
SMILES Kodhi:
O=C(N(C)C)C1=CC([C@@H](C)NC2=CC(F)=CC(F)=C2)=C3C(C(C=C(O3)N4CCOCC4) =O)=C1
InChi Code:
InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3 )9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14 -/m1/s1
InChi Key:
LMJFJIDLEAWOQJ-CQSZACIVSA-N
Keyword:
AZD8186, AZD-8186, AZD 8186, 1627494-13-6
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
AZD8186 iri uye inhibitor ye beta isoform ye phosphoinositide-3 kinase (PI3K), ine inogona kuita antineoplastic chiitiko. Pamusoro pekutonga, PI3Kbeta inhibitor AZD8186 inosarudza kuvharidzira basa rePI3Kbeta muPI3K/Akt/mTOR nzira yekusaina, izvo zvinogona kukonzera kudzikira kwebundu cell kuwanda. Iyo zvakare inokonzeresa kufa kwesero muPI3K-inoratidza cancer maseru. Nekunangisa kirasi I PI3K beta, mumiririri uyu anogona kunge achinyanya kushanda uye asina muchetura kupfuura pan PI3K inhibitors. PI3K-mediated siginecha inowanzo dhindwa mumaseru egomarara uye inobatsira kuwedzera bundu cell kukura, kupona, uye kuramba bundu kune akasiyana siyana antineoplastic agents. AZD8186 parizvino iri pasi pePase I miedzo yekiriniki.
Chinangwa: PI3K
