Vactosertib
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1300 |
| 5g | Mudura | 3800 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl )-2-fluoroaniline
SMILES Kodhi:
FC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
InChi Code:
InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12- 15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29 )
InChi Key:
FJCDSQATIJKQKA-UHFFFAOYSA-N
Keyword:
Vactosertib, EW-7197, EW7197, EW 7197, 1352608-82-2
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
Vactosertib, inozivikanwawo seEW-7197 ine simba ALK5 inhibitor. EW-7197 yakaratidza simba mu vivo anti-metastatic chiitiko, ichiratidza kugona kwayo kushandiswa senge anti-cancer therapy. EW-7197 inhibits TGF-β/Smad kusaina. EW-7197 inobvisa TGF-β1-induced tumor cell migration uye kupinda. EW-7197 inhibits cancer cancer metastasis kumapapu.EW-7197 inorebesa hupenyu hweBALB/c 4T1 mbeva kuburikidza nekuvharirwa kweEMT. EW-7197 inhibits metastasis uye inowedzera basa re cytotoxic T lymphocytes (CTLs) mu 4T1 orthotopic mbeva dzakabatanidzwa.
Chinangwa: ALK
