ARS-1620
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
100mg | Mudura | 800 |
500mg | Mudura | 1500 |
1g | Mudura | 2000 |
Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Kodhi:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
InChi Code:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Keyword:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
ARS-1620 iprodrug yakagadzirwa kubva kuARS-853, inova ine simba uye inosarudza S-IIP G12C inhibitor. ARS-1620 inotarisirwa kuve nzira yekurapa p.G12C KRAS mutant cancers.
Chinangwa: KRAS (K-Ras G12C)