ARS-1620

ARS-1620
  • Zita:ARS-1620
  • Catalog Nhamba:CPDB1588
  • Nhamba yeCAS:1698055-85-4
  • Molecular Weight:430.84
  • Chemical Formula:C21H17ClF2N4O2
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    100mg Mudura 800
    500mg Mudura 1500
    1g Mudura 2000
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

    SMILES Kodhi:

    C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl

    InChi Code:

    InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2

    InChi Key:

    QIQWMIZVWVSRAS-UHFFFAOYSA-N

    Keyword:

    ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

    Tsanangudzo:

    ARS-1620 iprodrug yakagadzirwa kubva kuARS-853, inova ine simba uye inosarudza S-IIP G12C inhibitor. ARS-1620 inotarisirwa kuve nzira yekurapa p.G12C KRAS mutant cancers.

    Chinangwa: KRAS (K-Ras G12C)


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