BAY-293

Igoa vaila'au:

(R) -6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

SMILES Code:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

InChi Code:

InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1

InChi Key:

WEGLOYDTDILXDA-OAHLLOKOSA-N

upu autu:

BAY-293,BAY 293,BAY293

Solubility: 

Teuina: 

Fa'amatalaga:

BAY-293 o se faʻamalosi malosi SOS1 e poloka ai le faʻagaioiina o le RAS e ala i le faʻalavelaveina o fegalegaleaiga RAS-SOS1. BAY-293) filifili faʻalavelave le fesoʻotaʻiga KRAS-SOS1 ma se IC50 o le 21 nM ma o se suʻesuʻega vailaʻau taua mo suʻesuʻega i le lumanaʻi.

Sini: SOS1 inhibitor