| Št. | Ime izdelka | Opis |
| CPD3611 | SB-204990 | SB-204990 je predzdravilo močnega inhibitorja citrat-liaze ATP SB-201076. SB-204990, ki so ga dajali peroralno podganam, se je absorbiral v sistemski obtok, farmakološko pomembne koncentracije SB-201076 so bile pridobljene v jetrih. SB-204990 (25 mg/kg na dan) je pri psu znižal tudi ravni holesterola v plazmi (za do 23 %) in trigliceridov (za do 38 %), pri čemer je prednostno znižal lipoprotein nizke gostote v primerjavi s holesterolom lipoproteina visoke gostote stopnje. SB-204990 je pomemben encim pri nadzoru oskrbe s substratom za novo sintezo lipidov in potencialna encimska tarča za hipolipidemično intervencijo. |
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