H3B-6527

Izina ryimiti:

N- (2 - (((6- (3- phenyl) acrylamide

Kode ya SMILES:

C = CC (NC1 = CC (N2CCN (CC) CC2) = CC = C1NC3 = NC = NC (N (C (NC4 = C (Cl) C) C (OC) = CC (OC) = C4Cl) = O) C) = C3) = O.

InChi Code:

InChI = 1S / C29H34Cl2N8O4 / c1-6-25 (40) 35-20-14-18 (39-12-10-38 (7-2) 11-13-39) 8-9-19 (20) 34- 23-16-24 (33-17-32-23) 37 (3 ) 29 (41) 36-28-26 (30) 21 (42-4) 15-22 (43-5) 27 (28) 31 / h6,8-9,14-17H, 1,7,10-13H2 , 2-5H3, (H, 35,40) (H, 36,41) (H, 32,33,34)

InChi Urufunguzo:

MBWRLLRCTIYXDW-UHFFFAOYSA-N

Ijambo ryibanze:

H3B-6527, H3B 6527, H3B6527, 1702259-66-2

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi).

Ibisobanuro:

H3B-6527 (H3 Biomedicine) ni inhibitori ya FGFR4 ihitamo cyane ibikorwa bya antitumour ikomeye muri FGF19 yongerewe umurongo wimbeba nimbeba.

Intego: FGFR4