EED226

Izina ryimiti:

N- (furan-2-ylmethyl) -8- (4- (methylsulfonyl) fenyl) - [1,2,4] triazolo [4,3-c] pyrimidin-5-amine

Kode ya SMILES:

O = S (C1 = CC = C (C2 = CN = C (NCC3 = CC = CO3) N4C2 = NN = C4) C = C1) (C) = O

InChi Code:

InChI = 1S / C17H15N5O3S / c1-26 (23,24) 14-6-4-12 (5-7-14) 15-10-19-17 (22-11-20-21-16 (15) 22) 18-9-13-3-2-8-25-13 / h2-8,10-11H, 9H2,1H3, (H, 18,19)

InChi Urufunguzo:

DYIRSNMPIZZNBK-UHFFFAOYSA-N

Ijambo ryibanze:

EED226, EED-226, EED 226, 2083627-02-3

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi).

Ibisobanuro:

E. Igabanya cyane ikimenyetso cya H3K27Me3 kwisi yose muri selile kandi ikagaragaza ingaruka zica selile zica selile zitwara heterozygous Y641N. EED226 ifite uburyo bworoshye nkuko byapimwe muri selile Caco-2 kuri A → B = 3.0x10-6 cm / s, hamwe na efflux kuri 7,6 [1].

Intego: EED226