Ozanimod

Izina ryimiti:

(S) -5- (3- (1 - ((2-hydroxyethyl) amin) -isopropoxybenzonitrile

Kode ya SMILES:

N # CC1 = CC (C2 = NC (C3 = CC = CC4 = C3CC [C @@ H] 4NCCO) = NO2) = CC = C1OC (C) C

InChi Code:

InChI = 1S / C23H24N4O3 / c1-14 (2) 29-21-9-6-15 (12-16 (21) 13-24) 23-26-22 (27-30-23) 19-5-3- 4-18-17 (19) 7-8-20 (18) 25-10-11-28 / h3-6,9,12,14,20,25,28H, 7-8,10-11H2,1- 2H3 / t20- / m0 / s1

InChi Urufunguzo:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

Ijambo ryibanze:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi).

Ibisobanuro:

Ozanimod ni moderi yatoranijwe, iboneka mumvugo ya sphingosine-1-fosifate (S1P) yakira S1P1 na SIP5. Itera imbere muri S1P1, igabanya kuzenguruka B na CCR7 (+) T lymphocytes, kandi igabanya ibipimo byindwara hamwe nindwara muburyo butatu bwindwara ziterwa na autoimmune.1 Ozanimod iri mubigeragezo byamavuriro kugirango isubiremo sclerose nyinshi na colitis ulcerative.

Intego: S1P