ARS-1323
Ibicuruzwa birambuye
Ibicuruzwa
| Ingano | Kuboneka | Igiciro (USD) |
| 100mg | Mububiko | 500 |
| 500mg | Mububiko | 800 |
| 1g | Mububiko | 1200 |
| Ingano nini | Shaka Amagambo | Shaka Amagambo |
Izina ryimiti:
1- (4- (6-chloro-8-fluoro-7- (2-fluoro-6-hydroxyphenyl) quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-imwe
Kode ya SMILES:
O = C (C = C) N1CCN (C2 = NC = NC3 = C2C = C (Cl) C (C4 = C (O) C = CC = C4F) = C3F) CC1
InChi Code:
InChI = 1S / C21H17ClF2N4O2 / c1-2-16 (30) 27-6-8-28 (9-7-27) 21-12-10-13 (22) 17 (19 (24) 20 (12) 25- 11-26-21) 18-14 (23) 4-3-5-15 (18) 29 / h2-5,10-11,29H, 1,6-9H2
InChi Urufunguzo:
ZRPZPNYZFSJUPA-UHFFFAOYSA-N
Ijambo ryibanze:
ARS1323, ARS 1323, ARS-1323, 1698024-73-5
Gukemura:Gukemura muri DMSO
Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)
Ibisobanuro:
ARS-1323 ni inhibitori ya mutant K-ras G12C yakuwe muri patenti WO 2015054572 A1. IC50 & Intego: K-Ras G12C
Intego: KRAS (K-Ras G12C)
