Alvocidib

Izina ryimiti:

2- (2-chlorophenyl) -5,7-dihydroxy-8 - ((3R, 4S) -3-hydroxy-1-methylpiperidin-4-yl) -4H-chromen-4-imwe

Kode ya SMILES:

O = C1C = C (C2 = CC = CC = C2Cl) OC3 = C ([C @ H] 4 [C @@ H] (O) CN (C) CC4) C (O) = CC (O) = C13

InChi Code:

InChI = 1S / C21H20ClNO5 / c1-23-7-6-12 (17 (27) 10-23) 19-14 (24) 8-15 (25) 20-16 (26) 9-18 (28-21 ( 19) 20) 11-4-2-3-5-13 (11) 22 / h2-5,8-9,12,17,24-25,27H, 6-7,10H2,1H3 / t12-, 17 + / m1 / s1

InChi Urufunguzo:

BIIVYFLTOXDAOV-PXAZEXFGSA-N

Ijambo ryibanze:

L 86-8275; L-868275; L 868275; L868275; HMR 1274; HMR-1274; HMR1274; Flavoperidol; Alvocidib

Gukemura: 

Ububiko: 

Ibisobanuro:

Alvocidib ni synthique N-methylpiperidinyl chlorophenyl flavone. Nkumwanya wa kinase iterwa na cyclin, alvocidib itera gufatwa kwingirangingo mu gukumira fosifora ya kinase iterwa na cyclin (CDKs) ndetse no kugabanya imvugo ya cyclin D1 na D3, bigatuma G1 itabwa muri yombi na apoptose. Iyi agent nayo irwanya irushanwa ryibikorwa bya adenosine triphosphate. Reba ibizamini bya clinique ikora cyangwa ibizamini bya clinique bifunze ukoresheje iyi agent.

Intego: CDK