TAS-120
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
Paketi Kukula | Kupezeka | Mtengo (USD) |
Dzina la Chemical:
1- [(3S)-3--[4-amino-3-[2-(3,5-dimethoxyphenyl) ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl] -1-pyrrolidinyl] -2-propen-1-imodzi
SMILES Kodi:
C=CC(N1C[C@@H](N2N=C(C#CC3=CC(OC)=CC(OC)=C3)C4=C(N)N=CN=C42)CC1)=O
InChi kodi:
InChI=1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28) 6-5-14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2 ,23,24,25)/t15-/m0/s1
InChi Key:
KEIPNCCJPRMIAX-HNNXBMFYSA-N
Mawu ofunika:
TAS-120
Kusungunuka:
Posungira:
Kufotokozera:
TAS-120 ndi orally bioavailable inhibitor ya fibroblast growth factor receptor (FGFR) yokhala ndi ntchito yoletsa antiineoplastic. FGFR inhibitor TAS-120 mosankha komanso mosasinthika imamangiriza ndi kuletsa FGFR, zomwe zingapangitse kuletsa kwa njira yopatsira ma siginecha ya FGFR ndi kuchuluka kwa maselo otupa, komanso kuchuluka kwa kufa kwa maselo mu FGFR-ma cell chotupa ochulukirapo. FGFR ndi receptor tyrosine kinase yofunikira pakuchulukira kwa maselo a chotupa, kusiyanitsa ndi kupulumuka ndipo mawonekedwe ake amayendetsedwa mumitundu yambiri yama cell chotupa.
Zolinga: FGFR