Mtengo wa IT-901
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
Paketi Kukula | Kupezeka | Mtengo (USD) |
100 mg | Zilipo | 500 |
500 mg | Zilipo | 800 |
1g | Zilipo | 1200 |
Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
5 - [(2,4-Dimethoxy-1-naphthalenyl) methylene]dihydro-2-thioxo-4,6 (1H,5H) -pyrimidinedione
SMILES Kodi:
O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S
InChi kodi:
InChI=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)
InChi Key:
JHOPCCOYRKEHQU-UHFFFAOYSA-N
Mawu ofunika:
IT-901, IT901, IT 901, 1584121-99-2
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
"IT-901 ndi c-Rel Inhibitor Yomwe Imagwirizanitsa Zinthu Zotsutsana ndi Kansa mu Hematologic Malignancies Poletsa Mayankho a NF-κB-Controlled Oxidative Stress Responses. IT-901 imalepheretsa mwamphamvu NF-κB subunit c-Rel. matenda opatsirana poteteza ntchito ya graft-versus-lymphoma pa nthawi ya allogeneic transplantation Kuwunika kowonjezereka kwa IT-901 pofuna kuchiza anthu a B-cell lymphoma mu m'galasi komanso mu vivo popanda choletsa ku NF-κB-dependent lymphoma. 901 sichinapangitse kuchuluka kwa mitundu yokhazikika ya okosijeni mu ma leukocyte wamba, kuwonetsa zomwe zimasankha khansara IT-901 ndi njira yochizira yochizira matenda amtundu wa lymphoid komanso kukulitsa matenda a graft-versus-host.
Cholinga: NF-kB