BLU-667

BLU-667
  • Dzina:BLU-667
  • Catalog No.:CPD2049
  • Nambala ya CAS:2097132-94-8
  • Kulemera kwa Molecular:532.27
  • Chemical formula:C28H33FN8O2
  • Zofufuza zasayansi zokha, osati za odwala.

    Tsatanetsatane wa Zamalonda

    Zolemba Zamalonda

    Paketi Kukula Kupezeka Mtengo (USD)

    Dzina la Chemical:

    (1s,4R)-N-((S)-1-(4-(4-fluoro-1H-pyrazol-1-yl)phenyl)ethyl)-1-methoxy-4-(4-methyl-6-( (5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexane-1-carboxamide

    SMILES Kodi:

    CC1=NC([C@@H]2CC[C@](C(N[C@@H](C)C3=CC=C(N4N=CC(F)=C4)C=C3)=O) (OC)CC2)=NC(NC5=NNC(C)=C5)=C1

    InChi kodi:

    InChI=1S/C28H33FN8O2/c1-17-13-24(33-25-14-18(2)35-36-25)34-26(31-17)21-9-11-28(39-4, 12-10-21)27(38)32-19(3)20-5-7-23(8-6-20)37-16-22(29)15-30-37/h5-8,13- 16,19,21H,9-12H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t19-,21-,28+/m0/s1

    InChi Key:

    HUQPYQIGHTXBNW-BDHWGLMFSA-N

    Mawu ofunika:

    BLU-667; BLU 667; BLU667

    Kusungunuka:DMSO

    Posungira: 

    Kufotokozera:

    BLU-667 ndi choletsa champhamvu komanso chosankha cha kusintha kwa RET, ma fusions, ndi zodziwikiratu zosagwira masinthidwe. Kuphatikizika kwa RET ndizomwe zimayendetsa makhansa angapo, kuphatikiza khansa ya m'mapapo ndi chithokomiro, ndipo kafukufuku wathu akuwonetsa kuti RET imagwiranso ntchito yofunika kwambiri pa khansa ya m'matumbo ndi m'mawere. Poyang'ana nthawi yomweyo dalaivala wamkulu komanso zosinthika zoloseredwa zomwe zimapangitsa kuti ma cell a khansa asamamve chithandizo ndi mankhwala ovomerezeka pano,

    Cholinga: RET


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