BAY-299
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3( 2H) -dione
SMILES Kodi:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
InChi kodi:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8- 4-7-16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6, 11H2,1-3H3
InChi Key:
OFWWWKUCDUISA-UHFFFAOYSA-N
Mawu ofunika:
BAY-299, BAY 299, BAY299, 2080306-23-4
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
BAY-299 ndi choletsa champhamvu komanso chosankha cha bromodomain ndi PHD chala chokhala ndi zala (BRPF) mapuloteni abanja BRD1 (IC50 = 6 nM), omwe amadziwikanso kuti BRPF2, ndi bromodomain yachiwiri ya transcription initiation factor TFIID subunits 1 (TAF1; IC50) = 13 nM).1 BAY-299 ndi >30-kusankha mowirikiza BRPF1, BRPF3, BRD9, ndi ATAD2 ndipo ndi>300-folds kusankha BRD4.
Cholinga: BRPF