ARS-1620
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 800 |
| 500 mg | Zilipo | 1500 |
| 1g | Zilipo | 2000 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Kodi:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
InChi kodi:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Mawu ofunika:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)
Kufotokozera:
ARS-1620 ndi mankhwala opangidwa kuchokera ku ARS-853, yomwe ndi yamphamvu komanso yosankha S-IIP G12C inhibitor. ARS-1620 ikuyembekezeka kukhala njira yochizira khansa ya p.G12C KRAS.
Cholinga: KRAS (K-Ras G12C)
