Verucerfont

Ingoa matū:

(S)-3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-(1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl)pyrazolo[1, 5-a] pyrimidin-7-amine

Waehere SMILES:

CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4

Waehere InChi:

InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28( 19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1

Kī InChi:

VKHVAUKFLBBZFJ-SFHVURJKSA-N

Kupumatua:

Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1

Wairewa:Wairewa i roto i te DMSO

Rokiroki:0 - 4°C mo te wa poto (ra ki nga wiki), -20°C ranei mo te wa roa (marama).

Whakaahuatanga:

"Ko Verucerfont, e mohiotia ana ko GSK561679 me NBI77860, he kaitukino CRF-1. Ka aukati a Verucerfont i te kaiwhakawhiwhi CRH-1, na reira ka whakaiti i te tukunga ACTH i muri i te ahotea roa. Kei te tirotirohia hei rongoa mo te waipiro, na te mea he maha nga wa e raru ai te ahotea. he take i roto i te whakawhanaketanga o te waipiro me te hokinga mai i te whakaora i te hunga inu waipiro kua whakaatuhia he hua pai i roto i nga rangahau kararehe engari kaore i whakamatauhia ki te tangata.

Whāinga: CRF-1