BAV-1895344

Nomen chemicum:

(R) -3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine

SMILES Code:

CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=CC=NN5)N=CC=C24.[H]Cl

InChi Code:

InChI=1S/C20H21N7O.ClH/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6- 21-20(19(14)24-18)16-4-7-22-25-16;/h3-8,11,13H,9-10,12H2,1-2H3(H,22,25) ;1H/t13-;/m1./s1

InChi Key:

KWQNBYGUBHMRPY-BTQNPOSSSA-N

Keyword:

1876467-74-1；CAS:1876467-74-1； CAS：1876467-74-1； BAY-1895344, BAY1895344, BAV 1895344

Solubilitas:Solutum in DMSO

Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

Descriptio:

BAV-1895344 est ATR selectivum ( interdum ataxia-telangiectasia et rad3 cognata ) inhibitor qui vetat multiplicationem latum spectri humani tumoris cellularum linearum (medianae IC50 = 78 nM). BAY-1895344 curationem aegris solidis tumoribus et lymphomatis provectis augetur, et est tentatio clinica subit periodum salutis et tolerabilitas pro aegris cancer.

Target: ATR