ND-630

ND-630
  • Nomen:ND-630
  • Catalogue No.CPD1592
  • CAS No.:1434635-54-7
  • Pondus hypotheticum:569.63
  • Formulae chemica:C28H31N3O8S
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    (R) -2-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl) -2,4-dioxo-1,2-dihydrothieno[2,3-d]pyrimidin-3(4H)-yl)-2-methylpropanamide

    SMILES Code:

    O=C(N)C(C)(C)N(C(N(C[C@@H](C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC= CO5)S3)=O)C4=O*

    InChi Code:

    InChI=1S/C28H31N3O8S/c1-16-21-24(32)31(28(2,3)26(33)34)27(35)30(25(21)40-22(16)23-29- 11-14-38-23)15-20(39-179-12-37-13-10-17)18-7-5-6-8-19(18)36-4/h5-8; 11,14,17,20H,9-10,12-13,15H2,1-4H3,(H,33,34)/t20-/m0/s1

    InChi Key:

    ZZWWXIBKLBMSCS-FQEVSTJZSA-N

    Keyword:

    ND-630, ND 630, GS-0976, GS0976, GS 0976, NDI-010976, NDI010976, NDI 010976, Firsocostat, 1434635-54-7

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    ND-630. Inhibitio convertitur et valde specifica pro ACC. ND-630 inhibet activitatem ACC inter se mutuo intra phosphopeptide-acceptantem et dimerizationem situm enzyme ad praecavendam dimerizationem. ND-630 inhibet synthesin acidum pingue cum EC50 nM in HepG2 cellularum LXVI sine mutando numerum cellularum totalis, interdum concentratio cellulosa, et incorporatio acetatis in cholesterolum.

    Target: ACC




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