Ertugliflozin

Nomen chemicum:

(1S,2S,3S,4R,5S) -5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1] octane-2,3 ,4-triol

SMILES Code:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3))(CO4)CO)O)O)O)Cl"

InChi Code:

"InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27 )18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18 -,19-,20+,21-,22-/m0/s1 "

InChi Key:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

Keyword:

Ertugliflozin, PF 04971729, MK-8835, 1210344-57-2

Solubilitas:Solutum in DMSO

Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

Descriptio:

Ertugliflozin, etiam nota ut PF-04971729, potens et selectivus inhibitor sodii-dependens glucosi cotransportator 2 et candidatus clinicus ad tractationem speciei 2 diabete melliti. studium clinicum demonstravit Ertugliflozin (1-25 mg/day) glycemicam potestatem emendasse, pondus corporis et pressuram sanguinis in patientibus cum T2DM suboptime in metformin moderatum, et bene toleratum est.

Target: SGLT-2