Omarigliptin
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Nomen chemicum:
(2R,3S,5R)-2-(2,5-difluorophenyl) -5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl) tetrahydro-2H -pyran-III-amine
SMILES Code:
N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1
InChi Code:
InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1
InChi Key:
MKMPWKUAHLTIBJ-ISTRZQFTSA-N
Keyword:
Omarigliptin, MK-3102, MK3102, Marizev,1226781-44-7
Solubilitas:Solutum in DMSO
Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)
Descriptio:
Omarigliptin, quae etiam MK-3102 nota est, potens et diu agendi DPP-IV inhibitor est pro semel-septimana tractatione 2 diabete generis. MK-3102 (omarigliptin), potentem ac selectivum dipeptidylum peptidase notus est 4 (DPP-4) inhibitor cum praeclaro pharmacokinetico profile obnoxio semel-septimani dosing humano et electo ut candidatus evolutionis clinicae. Omarigliptin nunc in 3 orci evolutione paschali est.
Target: DPP-4