EAI-045

Nomen chemicum:

2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide

SMILES Code:

O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O

InChi Code:

InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11- 3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)

InChi Key:

YTUFHOKUFOQRDF-UHFFFAOYSA-N

Keyword:

EAI-045, EAI045, EAI 045, 1942114-09-1

Solubilitas:Solutum in DMSO

Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)

Descriptio:

EAI045 ia^a potena et selectiva EGFR inhbitor. EAI045 scuta electa medicamento repugnant EGFR mutants sed receptori generis ferox parcit. EAI045 vetat L858R/T790M-mutantem EGFR cum potentia nanomolaria humili in pertentationibus diam.

Target: EGFR